Description: Dr. Cate Shanahan hits the Q&A hard, offering interesting commentary on a variety of topics, especially those relating to hormones and longevity markers. Cate explains how one’s level of elastin is a major predictor of lifespan. Elastin is typically considered an important component of healthy skin. Losing elastin and collagen (a form of elastin that is also a major element of healthy skin) cause wrinkles, an obvious sign of aging. Elastin, however, is present in other cells such as those in joints and arteries. Losing elastin accelerates aging (arteries become stiffer and less resilient; joints become creakier and less fluid) and hastens demise. Across species, the typical half-life of elastin is a lifespan predictor. For example, the half-life of elastin in a dog is 10 years whereas it’s 75 years in humans.